Structural Formula Vector Image
Title: Guaiapate
CAS Registry Number: 852-42-6
CAS Name: 1-[2-[2-[2-(2-Methoxyphenoxy)ethoxy]ethoxy]ethyl]piperidine
Manufacturers' Codes: MG-5454
Trademarks: Klamar (Maggioni)
Molecular Formula: C18H29NO4
Molecular Weight: 323.43
Percent Composition: C 66.84%, H 9.04%, N 4.33%, O 19.79%
Literature References: Basic ether deriv of guaiacol, q.v. Prepn: M. Carissimi, F. Ravenna, FR 1386633; eidem, US 3320254 (1965, 1967 both to Maggioni); M. Carissimi et al., J. Med. Chem. 8, 542 (1965). Pharmacological and clinical studies: G. Barbi, Gazz. Med. Ital. 127, 13 (1968). Analytical study: S. Cavicchi et al., Boll. Chim. Farm. 108, 682 (1969).
Properties: Liq, bp0.5 190-193°. LD50 i.p. in mice: 254 mmoles/kg (Carissimi).
Boiling point: bp0.5 190-193°
Toxicity data: LD50 i.p. in mice: 254 mmoles/kg (Carissimi)
Therap-Cat: Antitussive.
Keywords: Antitussive.
Status: This monograph has been retired and is no longer subject to revision or update.

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