Gallamine Triethiodide
Structural Formula Vector Image
Title: Gallamine Triethiodide
CAS Registry Number: 65-29-2
CAS Name: 2,2¢,2¢¢-[1,2,3-Benzenetriyltris(oxy)]tris[N,N,N-triethylethanaminium] triiodide
Additional Names: [n-phenenyltris(oxyethylene)]tris[triethylammonium triiodide]; 1,2,3-tris(2-triethylammonium ethoxy)benzene triiodide; 1,2,3-tris(2-diethylaminoethoxy)benzene tris(ethyl iodide); tri(b-diethylaminoethoxy)-1,2,3-benzene triiodoethylate; pyrogallol 1,2,3-(diethylaminoethyl ether) tris(ethyl iodide); benzcurine iodide
Manufacturers' Codes: RP-3697; F-2559
Trademarks: Relaxan (Hexal); Flaxedil (Aventis)
Molecular Formula: C30H60I3N3O3
Molecular Weight: 891.53
Percent Composition: C 40.42%, H 6.78%, I 42.70%, N 4.71%, O 5.38%
Literature References: Curarizing properties: D. Bovet et al., Compt. Rend. 225, 74 (1947); F. Depierre, ibid. 956. Prepn: E. Fourneau, US 2544076 (1951 to Rhone-Poulenc). Comparative clinical pharmacokinetics: W. Buzello, S. Agoston, Anaesthesist 27, 313 (1978). Mode of action: D. Colquhoun, R. E. Sheridan, Br. J. Pharmacol. 66, 78 (1979); eidem, Proc. R. Soc. London Ser. B 211, 181 (1981). Effects in mammalian and amphibian nerve fibers: K. J. Smith, C. L. Schauf, Science 212, 1170 (1981).
Properties: White cryst from acetone/water, mp 152-153° (indefinite). Freely sol in water, alc, dil acetone; sparingly sol in anhydr acetone, ether, benzene, chloroform.
Melting point: mp 152-153° (indefinite)
Therap-Cat: Neuromuscular blocking agent.
Therap-Cat-Vet: Neuromuscular blocking agent.
Keywords: Neuromuscular Blocking Agent; Nondepolarizing Agents.

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