Structural Formula Vector Image
Title: Fenoverine
CAS Registry Number: 37561-27-6
CAS Name: 10-[[4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl]acetyl]-10H-phenothiazine
Additional Names: 10-[4-(3,4-dioxymethylenebenzyl)-1-piperazinylacetyl]phenothiazine; 10-[(4-piperonyl-1-piperazinyl)acetyl]phenothiazine
Trademarks: Spasmopriv (Paillusseau)
Molecular Formula: C26H25N3O3S
Molecular Weight: 459.56
Percent Composition: C 67.95%, H 5.48%, N 9.14%, O 10.44%, S 6.98%
Literature References: Piperonylpiperazine derivative with spasmolytic activity. Prepn: A. Buzas, R. Pierre, FR 2092639 (1972), C.A. 77, 140143p (1972). Pharmacology, clinical studies in gastrointestinal disorders, dysmenorrhea: R. Pierre, R. Roustan, Med. Interne 15, 49 (1980). In treatment of colon dysfunction: Claudon, Rev. Fr. Gastro-Enterol. 198, 31 (1984).
Properties: Crystals from isopropyl ether, mp 141-142°. LD50 in mice (g/kg): ~1.50 orally, ~2.50 i.p. (Buzas, Pierre).
Melting point: mp 141-142°
Toxicity data: LD50 in mice (g/kg): ~1.50 orally, ~2.50 i.p. (Buzas, Pierre)
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic.

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