Structural Formula Vector Image
Title: Ethylmorphine
CAS Registry Number: 76-58-4
CAS Name: 7,8-Didehydro-4,5-epoxy-3-ethoxy-17-methylmorphinan-6-ol
Molecular Formula: C19H23NO3
Molecular Weight: 313.39
Percent Composition: C 72.82%, H 7.40%, N 4.47%, O 15.32%
Literature References: Prepd by ethylation of morphine: Baizer, Ellner, J. Am. Pharm. Assoc. 39, 581 (1950); Gorecki, Ann. Pharm. (Poznan) 7, 21 (1969). Toxicity data: M. Aurousseau, J. Navarro, Ann. Pharm. Fr. 15, 640 (1957).
Properties: Crystals from ethanol, mp 199-201°.
Melting point: mp 199-201°
Derivative Type: Hydrochloride dihydrate
CAS Registry Number: 6746-59-4
Trademarks: Codethyline (Houd?
Molecular Formula: C19H23NO3.HCl.2H2O
Molecular Weight: 385.88
Percent Composition: C 59.14%, H 7.31%, N 3.63%, O 20.73%, Cl 9.19%
Properties: White to faintly yellow crystalline powder, mp about 123° (dec); anhydrous form, mp about 170° (dec). One gram dissolves in 10 ml water and in 25 ml alcohol; slightly sol in chloroform, ether. LD50 in mice: 264.6 mg/kg s.c.; 0.771 g/kg orally (Aurousseau, Navarro).
Melting point: mp about 123° (dec); mp about 170° (dec)
Toxicity data: LD50 in mice: 264.6 mg/kg s.c.; 0.771 g/kg orally (Aurousseau, Navarro)
Derivative Type: Methiodide
CAS Registry Number: 6696-59-9
Additional Names: Ethyl-N-methylmorphinium iodide
Trademarks: Trachyl
Molecular Formula: C19H23NO3.CH3I
Molecular Weight: 455.33
Percent Composition: C 52.76%, H 5.76%, N 3.08%, O 10.54%, I 27.87%
NOTE: This is a controlled substance (opiate): 21 CFR, 1308.12.
Therap-Cat: Analgesic (narcotic); antitussive.
Therap-Cat-Vet: Analgesic (narcotic); antitussive; mydriatic.
Keywords: Analgesic (Narcotic); Antitussive.

Other Monographs:
1-Naphthyl SalicylateCambendazoleSulfamoxoleAjowan Oil
Zinc ThiocyanateBarium NitriteCyclocumarolEpiquinine
EnviroximeSamarium 153Sm LexidronamCholine EsteraseVitamin B12r
Fluosol DAMethyl AbietateSuccinonitrilen-Amyl Butyrate
©2006-2023 DrugFuture->Chemical Index Database