Structural Formula Vector Image
Title: Dynamin
Literature References: GTPase mechanoenzyme which plays an essential role in membrane budding and vesicle trafficking. Various isoforms which are tissue or function specific co-exist. Homotetramer which self-assembles into ring and spirals which form collars at the fission point. Isolation from bovine brain: H. S. Shpetner, R. B. Vallee, Cell 59, 421, (1989). Model for mechanism of membrane fission: M. M. Kozlov, Biophys. J. 77, 604 (1999). Review of function and nomenclature: R. Urrutia et al., Proc. Natl. Acad. Sci. USA 94, 377-384 (1997); of functions: M. A. McNiven et al., Trends Biochem. Sci. 25, 115-120 (2000). Review of structure and assembly: J. E. Hinshaw, Curr. Opin. Struct. Biol. 9, 260-267 (1999). Review of functional diversity and related dynamin-like proteins: A. M. van der Bliek, Trends Cell Biol. 9, 96-102 (1999).

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