Structural Formula Vector Image
Title: Dicyclomine
CAS Registry Number: 77-19-0
CAS Name: [1,1¢-Bicyclohexyl]-1-carboxylic acid 2-(diethylamino)ethyl ester
Additional Names: b-diethylaminoethyl 1-cyclohexylcyclohexanecarboxylate; bis(cyclohexyl)carboxylic acid diethylaminoethyl ester; dicycloverin
Molecular Formula: C19H35NO2
Molecular Weight: 309.49
Percent Composition: C 73.74%, H 11.40%, N 4.53%, O 10.34%
Literature References: Anticholinergic; binds to muscarinic M1 receptors. Prepn: C. H. Tilford et al., J. Am. Chem. Soc. 69, 2903 (1947); M. G. Van Campen, C. H. Tilford, US 2474796 (1949 to Merrell). Receptor binding study: H. Kilbinger, A. Stein, Br. J. Pharmacol. 94, 1270 (1988). Capillary GC determn in plasma: B. J. Walker et al., J. Chromatogr. 416, 150 (1987). Clinical trial in functional abdominal pain: M. G. Grillage et al., Br. J. Clin. Pract. 44, 176 (1990).
Derivative Type: Hydrochloride
CAS Registry Number: 67-92-5
Trademarks: Bentyl (Aventis); Bentylol (Aventis); Merbentyl (Aventis); Wyovin (Wyeth)
Molecular Formula: C19H35NO2.HCl
Molecular Weight: 345.95
Percent Composition: C 65.96%, H 10.49%, N 4.05%, O 9.25%, Cl 10.25%
Properties: Crystals from butanone, mp 164-166°. Bitter taste. Sol in water; freely sol in alcohol, chloroform; very slightly sol in ether.
Melting point: mp 164-166°
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic; Antimuscarinic.

Other Monographs:
n-Butyl AcetateFepradinolBazedoxifeneTaurolidine
TrietazineDiamthazole DihydrochlorideBarium Perchlorate9,10-Dibromoanthracene
FebarbamateVinylidene ChlorideCysteic AcidBeryllium Nitrate
Fentonium BromideOil of RoseCyclotheonamidesCarpetimycins
©2006-2023 DrugFuture->Chemical Index Database