Structural Formula Vector Image
Title: Cyclobendazole
CAS Registry Number: 31431-43-3
CAS Name: [5-(Cyclopropylcarbonyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester
Additional Names: ciclobendazole
Manufacturers' Codes: CC-2481; R-17147
Trademarks: Haptocil (Cilag-Chemie)
Molecular Formula: C13H13N3O3
Molecular Weight: 259.26
Percent Composition: C 60.22%, H 5.05%, N 16.21%, O 18.51%
Literature References: Prepn: J. L. Van Gelder et al., DE 2029637; eidem, US 3657267 (1971, 1972 both to Janssen). Synthesis and anthelmintic activity: A. H. M. Raeymaekers et al., Arzneim.-Forsch. 28, 586 (1978). Embryotoxic and antimitotic properties: P. Delatour, Y. Richard, Therapie 31, 505 (1976). Pharmacokinetics: R. R. Brodie et al., Arzneim.-Forsch. 27, 593 (1977). Biotransformation: B. C. Mayo et al., Drug Metab. Dispos. 6, 518 (1978). Clinical evaluation: A. Degrémont, E. Stahel, Schweiz. Med. Wochenschr. 108, 1430 (1978).
Properties: Crystals from acetic acid, mp 250.5°.
Melting point: mp 250.5°
Therap-Cat: Anthelmintic (Nematodes).
Keywords: Anthelmintic (Nematodes).

Other Monographs:
CholanthreneChlorpyrifosOxendolonen-Capric Acid
Cottonseed OilNicotineAmine 220Colesevelam Hydrochloride
Ethylene ChlorohydrinPhytantriolCarbipheneMoperone
Sodium DodecylbenzenesulfonateOlanzapinep-Chlorophenacyl BromideMethyl Chlorocarbonate
©2006-2021 DrugFuture->Chemical Index Database