Structural Formula Vector Image
Title: Clobenzorex
CAS Registry Number: 13364-32-4
CAS Name: (+)-N-[(2-Chlorophenyl)methyl]-a-methylbenzeneethanamine
Additional Names: (+)-N-(o-chlorobenzyl)-a-methylphenethylamine; d-N-(1-phenyl-2-propyl)-2-chlorobenzylamine
Molecular Formula: C16H18ClN
Molecular Weight: 259.77
Percent Composition: C 73.98%, H 6.98%, Cl 13.65%, N 5.39%
Literature References: Prepn and pharmacology: J. R. Boissier, R. Ratouis, FR 1429306 (1966 to Soc. Ind. Fabric. Antibiot.), C.A. 66, 46195h (1967); J. R. Boissier et al., Ann. Pharm. Fr. 24, 57 (1966). Synthesis of labelled compound: J. Lintermans et al., J. Labelled Compd. 6, 289 (1970). Metabolic studies: M. Thomasset et al., Experientia 26, 692 (1970); B. Glasson et al., Arzneim.-Forsch. 21, 1985 (1971).
Properties: bp0.1 132-134°.
Boiling point: bp0.1 132-134°
Derivative Type: Hydrochloride
CAS Registry Number: 5843-53-8
Manufacturers' Codes: Ba-7205; SD-271-12
Trademarks: Dinintel (Diamant); Rexigen (Bago)
Molecular Formula: C16H18ClN.HCl
Molecular Weight: 296.23
Percent Composition: C 64.87%, H 6.46%, Cl 23.94%, N 4.73%
Properties: Crystals, mp 182-183° (isopropanol). [a]D20 +26.3° (water). Sol in water, ethanol. Slightly sol in methanol, chloroform. LD50 i.p. in mice: 103 mg/kg (Boissier et al.).
Melting point: mp 182-183° (isopropanol)
Optical Rotation: [a]D20 +26.3° (water)
Toxicity data: LD50 i.p. in mice: 103 mg/kg (Boissier et al.)
Therap-Cat: Anorexic.
Keywords: Anorexic.

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