Structural Formula Vector Image
Title: Chlorazanil
CAS Registry Number: 500-42-5
CAS Name: N-(4-Chlorophenyl)-1,3,5-triazine-2,4-diamine
Additional Names: 2-amino-4-(p-chloroanilino)-s-triazine; N-(p-chlorophenyl)-2,4-diamino-s-triazine; 2-(p-chloroanilino)-4-amino-s-triazine; chlorazinil
Manufacturers' Codes: ASA-226
Trademarks: Diurazine; Triazurol; Orpizin; Neo-Urofort; Neurofort
Molecular Formula: C9H8ClN5
Molecular Weight: 221.65
Percent Composition: C 48.77%, H 3.64%, Cl 16.00%, N 31.60%
Literature References: Prepn: Clauder, Bulcsu, Magy. Kem. Foly. 57, 68 (1951), C.A. 46, 4023g (1952); AT 168063 (1951) and GB 676024 (1952), C.A. 47, 8097g, 3887i (1953). Synthesis and diuretic activity: Shah et al., J. Med. Chem. 11, 1167 (1968). See also Takagi, Ueda, Chem. Pharm. Bull. 17, 1061 (1969).
Properties: Crystals, mp 233-234°. Also reported as crystals from ethanol, mp 256-258° (Shah et al., loc. cit.).
Melting point: mp 233-234°; mp 256-258° (Shah et al., loc. cit.)
Derivative Type: Hydrochloride
CAS Registry Number: 2019-25-2
Trademarks: Daquin (3M Pharma); Doclizid-T; Orpidan (Heumann)
Molecular Formula: C9H8ClN5.HCl
Molecular Weight: 258.11
Percent Composition: C 41.88%, H 3.51%, Cl 27.47%, N 27.13%
Properties: mp 277-278°.
Melting point: mp 277-278°
Therap-Cat: Diuretic.
Keywords: Diuretic.
Status: This monograph has been retired and is no longer subject to revision or update.

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