Cabenegrins
Structural Formula Vector Image
Title: Cabenegrins
Literature References: Orally active antidotes against snake venoms; isolated from the root of a South American plant called "Cabeca de Negra" and structurally related to pterocarpin, q.v. Isoln: L. L. Darko et al., EP 89229; eidem, US 4429141 (1983, 1984 both to Richter, Budapest). Structure determn: M. Nakagawa et al., Tetrahedron Lett. 1982, 3855. Synthesis of (±)-cabenegrins A-I and A-II: M. Ishiguro et al., ibid. 3859.
 
Derivative Type: Cabenegrin A-I
CAS Registry Number: 84297-59-6
CAS Name: [6aR-[4(E),6aa,12aa]]-6a,12a-Dihydro-4-(4-hydroxy-3-methyl-2-butenyl)-6H-[1,3]dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-3-ol
Molecular Formula: C21H20O6
Molecular Weight: 368.38
Percent Composition: C 68.47%, H 5.47%, O 26.06%
Properties: White crystalline solid, mp 167-168°. uv max (ethanol): 309 nm (e 13000); uv max (methanol): 209, 233, 309 nm (e 75000, 24000, 13000).
Melting point: mp 167-168°
Absorption maximum: uv max (ethanol): 309 nm (e 13000); uv max (methanol): 209, 233, 309 nm (e 75000, 24000, 13000)
 
Derivative Type: Cabenegrin A-II
CAS Registry Number: 84297-60-9
CAS Name: 6a,12a-Dihydro-3-hydroxy-b-methyl-6H-[1,3]dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-2-butanol
Molecular Formula: C21H22O6
Molecular Weight: 370.40
Percent Composition: C 68.10%, H 5.99%, O 25.92%
Properties: uv max (methanol): 204, 230, 292, 308 nm (e 116000, 8000, 9400, 11800).
Absorption maximum: uv max (methanol): 204, 230, 292, 308 nm (e 116000, 8000, 9400, 11800)

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