Structural Formula Vector Image
Title: Bunamidine
CAS Registry Number: 3748-77-4
CAS Name: N,N-Dibutyl-4-(hexyloxy)-1-naphthalenecarboximidamide
Additional Names: N,N-dibutyl-4-hexyloxy-1-naphthamidine
Molecular Formula: C25H38N2O
Molecular Weight: 382.58
Percent Composition: C 78.48%, H 10.01%, N 7.32%, O 4.18%
Literature References: Prepn: NL 6403016 (1964 to Wellcome Found.), C.A. 62, 9083a (1965); NL 6603570 and FR M3766 (both 1966 to Wellcome Found.), C.A. 66, 37701t, 68911r (1967); M. Harfenist, R. Baltzly, US 3290375 (1966 to Burroughs-Wellcome). Review of synthesis, chemistry and activity: M. Harfenist et al., J. Med. Chem. 14, 97 (1971).
Derivative Type: Hydrochloride
CAS Registry Number: 1055-55-6
Trademarks: Scolaban (Cooper)
Molecular Formula: C25H38N2O.HCl
Molecular Weight: 419.04
Percent Composition: C 71.66%, H 9.38%, N 6.69%, O 3.82%, Cl 8.46%
Properties: Crystals from ethanol + ethyl acetate + ether, mp 214-214.8°. LD50 (calculated as base) orally in mice: 540 mg/kg (Harfenist, 1971).
Melting point: mp 214-214.8°
Toxicity data: LD50 (calculated as base) orally in mice: 540 mg/kg (Harfenist, 1971)
Derivative Type: 3-Hydroxy-2-naphthoate
Trademarks: Buban (Burroughs Wellcome)
Properties: mp 169-170°.
Melting point: mp 169-170°
Therap-Cat-Vet: Anthelmintic (Cestodes).
Status: This monograph has been retired and is no longer subject to revision or update.

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