Benzylmorphine
Structural Formula Vector Image
Title: Benzylmorphine
CAS Registry Number: 14297-87-1
CAS Name: 7,8-Didehydro-4,5-epoxy-17-methyl-3-(phenylmethoxy)morphinan-6-ol
Molecular Formula: C24H25NO3
Molecular Weight: 375.46
Percent Composition: C 76.77%, H 6.71%, N 3.73%, O 12.78%
Literature References: Prepn from morphine and benzyl chloride in the presence of sodium ethylate: DE 91813 (1897 to E. Merck), Frdl. 4, 1245; from morphine and benzyldimethylphenylammonium hydroxide: Rodionow, Bull. Soc. Chim. Fr. [4] 45, 109 (1929). Properties of hydrochloride: Dott, Pharm. J. 115, 757 (1925).
Properties: Needles from water, prisms or platelets from ether, chloroform. mp 132°. Soluble in 2500 parts cold water, more sol in boiling water; 1.6 parts dissolves in 100 parts ether; readily sol in 50% alcohol, benzene.
Melting point: mp 132°
 
Derivative Type: Hydrochloride
Additional Names: Peronine
Molecular Formula: C24H25NO3.HCl
Molecular Weight: 411.92
Percent Composition: C 69.98%, H 6.36%, N 3.40%, O 11.65%, Cl 8.61%
Properties: Monohydrate, needles from water. Sol at 15° in 133 parts water, 218 parts 95% alcohol, 390 parts chloroform, 100 parts methanol; slightly sol in abs alcohol; very slightly sol in ether, acetone, isoamyl alcohol.
 
NOTE: This is a controlled substance (opium derivative): 21 CFR, 1308.11.
Therap-Cat: Analgesic (narcotic).
Keywords: Analgesic (Narcotic).

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