Benztropine Mesylate
Structural Formula Vector Image
Title: Benztropine Mesylate
CAS Registry Number: 132-17-2
CAS Name: 3-(Diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane methanesulfonate
Additional Names: 3a-(diphenylmethoxy)-1aH,5aH-tropane methanesulfonate; benztropine methanesulfonate; tropine benzohydryl ether methanesulfonate
Trademarks: Cogentin (Merck & Co.); Cogentinol (Astra)
Molecular Formula: C22H29NO4S
Molecular Weight: 403.53
Percent Composition: C 65.48%, H 7.24%, N 3.47%, O 15.86%, S 7.95%
Literature References: Anticholinergic. Prepd by the action of diphenyldiazomethane on tropine: Phillips, US 2595405 (1952 to Merck & Co.). Crystal structure: P. G. Jones et al., Acta Crystallogr. B34, 3125 (1978).
Properties: Crystals from acetone + ether, mp 143°. uv max: 259 nm (EM = 437). Soluble in water. pH about 6.
Melting point: mp 143°
Absorption maximum: uv max: 259 nm (EM = 437)
Therap-Cat: Antiparkinsonian.
Keywords: Antiparkinsonian; Antimuscarinic.

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