Structural Formula Vector Image
Title: Alibendol
CAS Registry Number: 26750-81-2
CAS Name: 2-Hydroxy-N-(2-hydroxyethyl)-3-methoxy-5-(2-propenyl)benzamide
Additional Names: 5-allyl-2-hydroxy-N-(2-hydroxyethyl)-m-anisamide; 2-hydroxy-3-methoxy-5-allyl-N-(b-hydroxyethyl)benzamide
Manufacturers' Codes: EB-1856; FC-54; H-3774
Trademarks: Cebera (Irex)
Molecular Formula: C13H17NO4
Molecular Weight: 251.28
Percent Composition: C 62.14%, H 6.82%, N 5.57%, O 25.47%
Literature References: Amide analog of eugenol, q.v. Prepn: FR 1584715; F. Clémence, O. Le Martret, US 3668238 (1967, 1972 both to Roussel). Synthesis and pharmacologic activity: F. Clémence et al., Chim. Ther. 5, 188 (1970).
Properties: Crystals from benzene, mp 95°. uv max (ethanol): 316, 218 nm. LD50 in Swiss male mice (mg/kg): >3000 orally; >2000 s.c.; 209 i.p.; 217 i.v. (Clémence).
Melting point: mp 95°
Absorption maximum: uv max (ethanol): 316, 218 nm
Toxicity data: LD50 in Swiss male mice (mg/kg): >3000 orally; >2000 s.c.; 209 i.p.; 217 i.v. (Clémence)
Therap-Cat: Choleretic; antispasmodic.
Keywords: Antispasmodic; Choleretic.

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