8-Hydroxy-7-iodo-5-quinolinesulfonic Acid
Structural Formula Vector Image
Title: 8-Hydroxy-7-iodo-5-quinolinesulfonic Acid
CAS Registry Number: 547-91-1
Additional Names: 7-Iodo-8-hydroxyquinoline-5-sulfonic acid; m-iodo-o-hydroxyquinolineanasulfonic acid
Trademarks: Ferron; Loretin
Molecular Formula: C9H6INO4S
Molecular Weight: 351.12
Percent Composition: C 30.79%, H 1.72%, I 36.14%, N 3.99%, O 18.23%, S 9.13%
Literature References: Obtained from the potassium salt of 8-hydroxy-5-quinolinesulfonic acid by the action of KI, bleaching powder, and HCl: Claus, Arch. Pharm. 231, 704 (1893); DE 72942 (1893); by the action of KI and Ca(OCl)2 on 8-hydroxy-5-quinolinesulfonic acid: Botton, C.A. 52, 18407e (1958).
Properties: Sulfur yellow, almost odorless and tasteless, crystalline powder. mp 260-270° (dec). One gram dissolves in 500 ml cold, 170 ml boiling water; slightly sol in alcohol. Practically insol in ether or oils.
Melting point: mp 260-270° (dec)
 
Derivative Type: Compd with chloroquine (2:1)
CAS Registry Number: 7270-12-4
Additional Names: Chloquinate; chlochinate; cloquinate
Trademarks: Resotren (Bayer)
Literature References: Prepn: Koenig, Andersag, US 2650224 (1953 to Schenley Industries).
 
Derivative Type: Mixture of 80% of 8-hydroxy-7-iodo-5-quinolinesulfonic acid and 20% sodium bicarbonate
Additional Names: Chiniofon; quiniofon
Trademarks: Quinoxyl (Burroughs Wellcome); Sefona; Yatren (Bayer); Yochinol
 
Use: As colorimetric reagent for ferric ion.
Therap-Cat: Antiamebic; antiseptic.
Keywords: Antiamebic.

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