Benzyl Benzoate
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C14H12O2 212.24

Benzoic acid, phenylmethyl ester.
Benzyl benzoate [120-51-4].
» Benzyl Benzoate contains not less than 99.0 percent and not more than 100.5 percent of C14H12O2.
Packaging and storage— Preserve in tight, well-filled, light-resistant containers, and avoid exposure to excessive heat.
Specific gravity 841: between 1.116 and 1.120.
Congealing temperature 651: not lower than 18.0. Congelation may be brought about by addition of a fragment of previously congealed Benzyl Benzoate when the temperature has reached the expected congealing temperature.
Refractive index 831: between 1.568 and 1.570 at 20.
Aldehyde— Transfer 10.0 g to a 125-mL conical flask containing 50 mL of alcohol and 5 mL of hydroxylamine hydrochloride solution (3.5 in 100), mix, and allow to stand for 10 minutes. Add 1 mL of bromophenol blue TS, and titrate with 0.1 N sodium hydroxide VS to a light green endpoint. Perform a blank determination, and match the color of the endpoint with that of the titrated test solution. The net volume of 0.1 N sodium hydroxide consumed does not exceed 0.50 mL (0.05% as benzaldehyde).
Acidity— Add 2 drops of phenolphthalein TS to 25 mL of alcohol, and add 0.020 N sodium hydroxide until a pink color is produced. Add 5.0 g of Benzyl Benzoate, mix, and titrate with 0.020 N sodium hydroxide: not more than 1.5 mL of 0.020 N sodium hydroxide is required to restore the pink color.
Assay— Transfer about 2 g of Benzyl Benzoate, accurately weighed, to a conical flask fitted with a reflux condenser, add 50.0 mL of 0.5 N alcoholic potassium hydroxide VS, and boil gently for 1 hour. Cool, add phenolphthalein TS, and titrate with 0.5 N hydrochloric acid VS. Perform a blank determination (see Residual Titrations under Titrimetry 541). Each mL of 0.5 N alcoholic potassium hydroxide is equivalent to 106.1 mg of C14H12O2.
Auxiliary Information— Please check for your question in the FAQs before contacting USP.
Topic/Question Contact Expert Committee
Monograph Behnam Davani, Ph.D., M.B.A.
Senior Scientist
(MDAA05) Monograph Development-Antivirals and Antimicrobials
Reference Standards Lili Wang, Technical Services Scientist
USP32–NF27 Page 1652
Chromatographic Column—
Chromatographic columns text is not derived from, and not part of, USP 32 or NF 27.