Polyoxyl 35 Castor Oil
» Polyoxyl 35 Castor Oil contains mainly the tri-ricinoleate ester of ethoxylated glycerol, with smaller amounts of polyethylene glycol ricinoleate and the corresponding free glycols. It results from the reaction of glycerol ricinoleate with about 35 moles of ethylene oxide.
Packaging and storage—
Preserve in tight containers.
Identification—
B:
Dissolve about 0.1 g in 10 mL of alcoholic potassium hydroxide TS, boil for about 3 minutes, and evaporate to dryness. Mix the residue with 5 mL of water: it dissolves, yielding a clear solution. Add a few drops of glacial acetic acid: a white precipitate is formed.
C:
To a solution (1 in 20) add bromine TS, dropwise: the bromine is decolorized.
Specific gravity 
841
:
between 1.05 and 1.06.
841:
between 1.05 and 1.06.
Viscosity 911:
between 600 and 850 centipoises at 25
, a capillary viscometer being used.
911:
between 600 and 850 centipoises at 25, a capillary viscometer being used.
Acid value 401:
not more than 2.0.
401:
not more than 2.0.
Hydroxyl value 401:
between 65 and 80.
401:
between 65 and 80.
Iodine value 401:
between 25 and 35.
401:
between 25 and 35.
Saponification value 401:
between 60 and 75.
401:
between 60 and 75.
Water, Method I 921:
not more than 3.0%.
921:
not more than 3.0%.
Residue on ignition 281:
not more than 0.3%.
281:
not more than 0.3%.
Heavy metals, Method II 231:
0.001%.
231:
0.001%.
Auxiliary Information—
Please check for your question in the FAQs before contacting USP.
Chromatographic Column—
| Topic/Question | Contact | Expert Committee |
| Monograph | Hong Wang, Ph.D.
Scientist 1-301-816-8351 |
(EM205) Excipient Monographs 2 |
| Reference Standards | Lili Wang, Technical Services Scientist 1-301-816-8129 RSTech@usp.org |
USP32–NF27 Page 1316
Pharmacopeial Forum: Volume No. 31(6) Page 1671
Chromatographic columns text is not derived from, and not part of, USP 32 or NF 27.