for solid packaged in single-unit containers: meets the requirements.

Mobile phase and Chromatographic system—Proceed as directed in the Assay under Oxacillin Sodium.

Diluent— Prepare a mixture of water and acetonitrile (700:300).

Standard preparation— Prepare a solution of USP Oxacillin Sodium RS in Diluent having a known concentration of about 0.11 mg per mL. [note—Use this solution on the day prepared.]

Assay preparation— Transfer an accurately measured volume of Oxacillin Sodium for Oral Solution, constituted as directed in the labeling, equivalent to about 250 mg of oxacillin (C19H19N3O5S), to a 250-mL volumetric flask, dilute with water to volume, and mix. Transfer 5.0 mL of this solution to a 50-mL volumetric flask, dilute with Diluent to volume, and mix. Filter about 5 mL of this solution through a 0.5-µm or finer porosity filter, discarding the first 2 mL of the filtrate. Use the clear filtrate as the Assay preparation. [note—Use this Assay preparation on the day prepared.]

Procedure— Proceed as directed for Procedure in the Assay under Oxacillin Sodium. Calculate the quantity, in mg, of oxacillin (C19H19N3O5S) in each mL of the constituted Oxacillin Sodium for Oral Solution taken by the formula: in which V is the volume, in mL, of the constituted Oxacillin Sodium for Oral Solution taken, and the other terms are as defined therein.