Cellulose, 2-hydroxyethyl ether [9004-62-0].
» Hydroxyethyl Cellulose is a partially substituted poly(hydroxyethyl) ether of cellulose. It is available in several grades, varying in viscosity and degree of substitution, and some grades are modified to improve their dispersion in water. It may contain suitable anticaking agents.
Packaging and storage Preserve in well-closed containers.
Labeling The labeling indicates its viscosity, under specified conditions, in aqueous solution. The indicated viscosity may be in the form of a range encompassing 50% to 150% of the average value.
A: Stir about 1 g into 100 mL of water: it is dissolved completely to produce a colloidal solution that remains clear when heated to 60.
B: Place 1 mL of the solution from Identification test A on a glass plate, and allow the water to evaporate: a thin, self-sustaining film is formed.
C: To 1 mL of a solution (1 in 2000) add 1 mL of phenol solution (1 in 20). Add 5 mL of sulfuric acid, shake, and allow to cool: the color of the solution so obtained becomes orange.
Viscosity 911 When determined at the concentration and under the conditions specified in the labeling, its viscosity is not less than 50% and not more than 150% of the labeled viscosity, where stated as a single value, or it is between the maximum and minimum values, where stated as a range of viscosities.
pH 791: between 6.0 and 8.5, in a solution (1 in 100).
Loss on drying 731 Dry it at 105 for 3 hours: it loses not more than 10.0% of its weight.
Residue on ignition 281: not more than 5.0%.
Lead 251: 0.001%.
Heavy metals, Method II 231: 20 µg per g.
Auxiliary Information Please check for your question in the FAQs before contacting USP.Chromatographic Column
USP32NF27 Page 1250Pharmacopeial Forum: Volume No. 34(6) Page 1595
Chromatographic columns text is not derived from, and not part of, USP 32 or NF 27.