» Diethyl Phthalate contains not less than 98.0 percent and not more than 102.0 percent of C12H14O4, calculated on the anhydrous basis.
Packaging and storage Preserve in tight containers.
Identification, Infrared Absorption 197F, on undried specimen.
Specific gravity 841: between 1.118 and 1.122, at 20.
Refractive index 831: between 1.500 and 1.505, at 20.
Acidity Mix 20.0 g with 50 mL of alcohol that previously has been neutralized to a phenolphthalein endpoint, and titrate with 0.10 N sodium hydroxide to a phenolphthalein endpoint: not more than 0.50 mL is required for neutralization.
Water, Method I 921: not more than 0.2%.
Residue on ignition 281 Heat gently about 10 g, accurately weighed, until the liquid has evaporated, and ignite the residue to constant weight. Not more than 0.02% is found.
Assay Transfer about 1.5 g of Diethyl Phthalate, accurately weighed, to a flask, add 50.0 mL of 0.5 N alcoholic potassium hydroxide VS, attach a reflux condenser to the flask, and boil on a water bath for 1 hour. Add 20 mL of water, then add phenolphthalein TS, and titrate the excess potassium hydroxide with 0.5 N hydrochloric acid VS. Perform a blank determination (see Residual Titrations under Titrimetry 541). Each mL of 0.5 N potassium hydroxide is equivalent to 55.56 mg of C12H14O4.
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USP32NF27 Page 1226