• British Pharmacopoeia Volume III
  • Formulated Preparations: Specific Monographs

Ammonium Chloride Mixture

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General Notices

Ammonium Chloride Oral Solution

Definition

Ammonium Chloride Mixture is an oral solution containing 10% w/v of Ammonium Chloride in a suitable vehicle containing Aromatic Ammonia Solution and Liquorice Liquid Extract.

Extemporaneous preparation

It is recently prepared according to the following formula.

Ammonium Chloride

100 g

Aromatic Ammonia Solution

50 mL

Liquorice Liquid Extract

100 mL

Water

Sufficient to produce 1000 mL

The mixture complies with the requirements stated under Oral Liquids and with the following requirements.

Content of ammonium chloride, NH4Cl

9.50 to 10.66% w/v.

Assay

To 1 mL add 20 mL of water and titrate with 0.1m silver nitrate VS determining the end point potentiometrically. Each mL of 0.1m silver nitrate VS is equivalent to 5.349 mg of NH4Cl.