• British Pharmacopoeia Volume III
  • Formulated Preparations: Specific Monographs

Calamine and Coal Tar Ointment

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General Notices

Compound Calamine Ointment

Definition

Calamine and Coal Tar Ointment contains 12.5% w/w each of Calamine and Zinc Oxide and 2.5% w/w of Strong Coal Tar Solution in a suitable water-emulsifying basis.

Extemporaneous preparation

The following formula and directions apply.

Calamine, finely sifted

125 g

Zinc Oxide, finely sifted

125 g

Strong Coal Tar Solution

25 g

Hydrous Wool Fat

250 g

White Soft Paraffin

475 g

Melt together the Hydrous Wool Fat and the White Soft Paraffin. Triturate the Calamine and Zinc Oxide in the melted basis and stir gently, when cooled, to about 40°. Gradually incorporate the Strong Coal Tar Solution and stir until cold.

The ointment complies with the requirements stated under Topical Semi-solid Preparations and with the following requirements.

Content of zinc compounds, calculated as ZnO

19.8 to 22.8% w/w.

Identification

The residue obtained in the Assay is yellow when hot and white when cool.

Assay

Gently heat 1 g until the basis is completely volatilised or charred. Increase the heat until the carbon is removed and ignite the residue of ZnO until, after further ignition, two successive weighings do not differ by more than 0.2% of the weight of the residue. Each g of residue is equivalent to 0.8034 g of Zn.

Storage

Calamine and Coal Tar Ointment should be kept in a container that minimises evaporation losses.