FDA药品溶出方法数据库
(FDA-Recommended Dissolution Methods Database)
药品通用名称 剂型 USP溶出装置 速度 溶出介质 介质体积 建议取样时间(分钟) 更新日期
Venlafaxine Besylate Tablet (Extended Release) II (Paddle with sinker) 50 0.1 M NaCl in water (Degassed) 900 1, 2, 4, 6, 8, 12, 14 and 16 hours 2023/02/09
Venlafaxine HCl Capsule (Extended Release) Develop a dissolution method 2023/09/15
Venlafaxine HCl Tablet (Extended Release) Develop a dissolution method 2023/09/15
Venlafaxine HCl Tablet Refer to FDA's Dissolution Guidance, 2018 2020/07/02
Verapamil HCl Capsule (Extended Release) Refer to USP 2015/08/27
Verapamil HCl Tablet (Extended Release) Refer to USP 2010/06/24
Verapamil HCl Tablet Refer to USP 2008/11/04
Vericiguat Tablet II (Paddle) 75 0.01 N HCl, pH 2.0 900 5, 10, 15, 20 and 30 2022/07/07
Verteporfin Injectable Develop a method to characterize in vitro release. 2014/08/14
Vibegron Tablet Refer to FDA's Dissolution Guidance, 2018 2023/02/09
Vigabatrin Tablet Refer to FDA's Dissolution Guidance, 2018 2020/07/02
Vilazodone HCl Tablet II (Paddle) 60 0.1% v/v Glacial acetic acid solution (pH 3.1) 1000 10, 15, 20, 30 and 45 2014/08/14
Viloxazine HCl Capsule (Extended Release) II (Paddle) with sinker 50 pH 6.8 Phosphate Buffer 900 1, 2, 4, 6, 8, 10, 12 and 16 hours 2022/07/07
Vismodegib Capsule II (Paddle) 75 0.01 N HCl with 1.0% sodium lauryl sulfate (SLS) 900 10, 15, 20, 30 and 45 2015/05/28
Voclosporin Capsule II (Paddle) 75 0.75% of Polyoxyl 40 hydrogenated castor oil in sodium acetate buffer (22mM), pH 4.5 900 10, 20, 30, 45 and 60 2023/02/09
Vorapaxar Sulfate Tablet II (Paddle) 50 41 mM Na2HPO4, 1.5% Citric Acid, pH 3.0 ± 0.5 900 5, 10, 20, 30, 45 and 60 2015/12/24
Voriconazole Suspension II (Paddle) 50 0.1 N HCl 900 10, 20, 30 and 45 2007/01/03
Voriconazole Tablet II (Paddle) 50 0.1 N HCl 900 10, 20, 30 and 45 2008/11/25
Vorinostat Capsule Develop a dissolution method 2023/09/15
Vortioxetine HBr Tablet II (Paddle) 50 0.1 N HCl 900 10, 15, 20, 30 and 45 2015/05/28

数据库说明:

当前数据更新日期:2024年05月20日。
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