*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM6408000
CHEMICAL NAME           : 4-Piperidinecarboxylic acid,
                          4-phenyl-1-(2-(phenylamino)ethyl)-, ethyl ester
CAS REGISTRY NUMBER     : 13830-05-2
BEILSTEIN REFERENCE NO. : 0327208
REFERENCE               : 4-22-00-01034 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H28-N2-O2
MOLECULAR WEIGHT        : 352.52
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ethyl 4-phenyl-1-(2-(phenylamino)ethyl)piperidine-4-carboxylate
   * Isonipecotic acid, 1-(2-anilinoethyl)-4-phenyl-, ethyl ester
   * 4-Phenyl-1-(2-(phenylamino)ethyl)-4-piperidinecarboxylic acid ethyl ester
   * WIN 13,797
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 175 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   3,358,1961
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 39 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   3,358,1961
 
                            *** END OF RECORD ***