*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM7340093
CHEMICAL NAME           : 3,4-Piperidinediol,
                          1,3-dimethyl-6-(4-methoxyphenyl)-, hydrochloride,
                          (3-alpha,4-beta,6-beta)-
CAS REGISTRY NUMBER     : 67261-54-5
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H21-N-O3.Cl-H
MOLECULAR WEIGHT        : 287.82
WISWESSER LINE NOTATION : T6NTJ A1 BR DO1& DQ EQ E1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (3-alpha,4-beta,6-beta)-1,3-Dimethyl-6-(4-methoxyphenyl)-3,4-piperidined
     iol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 753 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 41,128,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 169 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   KHFZAN Khimiko-Farmatsevticheskii Zhurnal.  Chemical Pharmaceutical Journal.
    For English translation, see PCJOAU.  (V/O Mezhdunarodnaya Kniga, 113095
   Moscow, USSR)  V.1-    1967-  Volume(issue)/page/year: 24(2),114,1990
 
                            *** END OF RECORD ***