*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM7165000
CHEMICAL NAME           : Piperidine,
                          4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4
                          -ylidene)-1-methyl-
CAS REGISTRY NUMBER     : 15574-96-6
BEILSTEIN REFERENCE NO. : 0753534
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H21-N-S
MOLECULAR WEIGHT        : 295.47
WISWESSER LINE NOTATION : T C576 BY FS&T&J BU- DT6N DYTJ A1
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * BC 105
   * Litec
   * Pizotifen
   * Pizotyline
   * Sandomigram
   * Sandomygran
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 12857 ug/kg/12D-I
TOXIC EFFECTS :
   Liver - jaundice, other or unclassified
REFERENCE :
   AIMDAP Archives of Internal Medicine.  (AMA, 535 N. Dearborn St., Chicago,
   IL 60610)  V.1-    1908-  Volume(issue)/page/year: 144,815,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 410 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHMCAA Pharmacologist.  (American Soc. for Pharmacology and Experimental
   Therapeutics, 9650 Rockville Pike, Bethesda, MD 20014)  V.1-    1959-
   Volume(issue)/page/year: 12,297,1970
 
                            *** END OF RECORD ***