*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM6076000
CHEMICAL NAME           : 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-
CAS REGISTRY NUMBER     : 15883-20-2
BEILSTEIN REFERENCE NO. : 0206391
REFERENCE               : 4-22-00-00098 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H20-N2-O
MOLECULAR WEIGHT        : 232.36
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide
   * Demethylmepivacaine
   * Debutylbupivacaine
   * Desbutylbupivacaine
   * N-Desbutylbupivacaine
   * 2',6'-Pipecoloxylidide
   * 2',6'-Pipecolylxylidine
   * Piperidine-2-carboxylic acid 2,6-dimethylanilide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CEXPB9 Clinical and Experimental Pharmacology and Physiology.  (Blackwell
   Scientific Publications, (Australia) Pty Ltd., 107 Barry St., Carlton, Vic.
   3053, Australia)  V.1-  1974-  Volume(issue)/page/year: 21,997,1994
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #0155176
 
                            *** END OF RECORD ***