*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM4924400
CHEMICAL NAME           : Piperidine,
                          1-(3-(bis(2-chloroethyl)amino)-p-toluoyl)-
CAS REGISTRY NUMBER     : 21447-87-0
LAST UPDATED            : 199307
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H24-Cl2-N2-O
MOLECULAR WEIGHT        : 343.33
WISWESSER LINE NOTATION : T6NTJ AVR D1 CN2G2G
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(3-(Bis(2-chloroethyl)amino)-p-toluoyl)piperidine
   * 3-(Bis(2-chloroethyl)amino)-p-tolyl piperidyl ketone
   * Ketone, 3-(bis(2-chloroethyl)amino)-p-tolyl piperidyl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CTRRDO Cancer Treatment Reports.  (Washington, DC)  V.60-71, 1976-87.  For
   publisher information,  see JNCIEQ.  Volume(issue)/page/year: 62,2045,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 12,161,1969
 
                            *** END OF RECORD ***