*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM3084900
CHEMICAL NAME           : Piperazinium,
                          1-(3-(2-chlorophenothiazin-10-yl)propyl)-1,4-dimethyl
                          -4-(2-hydroxyethyl)-, diiodide
CAS REGISTRY NUMBER     : 26718-20-7
LAST UPDATED            : 198906
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C23-H32-Cl-N3-O-S.2I
MOLECULAR WEIGHT        : 687.89
SYNONYMS/TRADE NAMES :
   *   1-(3-(2-Chlorophenothiazin-10-yl)propyl)-1,4-dimethyl-4-(2-hydroxyethyl)
     piperazinium 2I
   * Perphenazine dimethiodide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18200 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - cyanosis
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 59,976,1970
 
                            *** END OF RECORD ***