*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM3407960
CHEMICAL NAME           : 2-Piperazinone,
                          1-((4,4-dimethyl-4H-1,3-benzothiazin-2-yl)methyl)-3-p
                          henyl-, oxalate
CAS REGISTRY NUMBER     : 81735-48-0
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H23-N3-O-S.C2-H2-O4
MOLECULAR WEIGHT        : 455.57
WISWESSER LINE NOTATION : T66 BS DN EHJ C1- AT6NV DNTJ CR& E1 E1 &QVVQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-((4,4-Dimethyl-4H-1,3-benzothiazin-2-yl)methyl)-3-phenyl-2-piperazinone 
    oxalate
   * 2-(2'-Oxo-3'-phenylpiperazino)methyl-4,4-dimethyl-4H-1,3-benzothiazine  
   oxalate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 45,64,1982
 
                            *** END OF RECORD ***