*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM2672000
CHEMICAL NAME           : 1-Piperazinepropanol,
                          4-(2-ethyl-7-fluoro-10H-thieno(2,3-b)(1,5)benzodiazep
                          in-4-yl)-
CAS REGISTRY NUMBER     : 61326-14-5
BEILSTEIN REFERENCE NO. : 1044595
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H25-F-N4-O-S
MOLECULAR WEIGHT        : 388.55
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-Ethyl-7-fluoro-4-(4-(3-hydroxypropyl)-1-piperazinyl)-10H-thieno(2,3-b)
     (1,5)benzodiazepine
   *   4-(2-Ethyl-7-fluoro-10H-thieno(2,3-b)(1,5)benzodiazepin-4-yl)-1-piperazi
     nepropanol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 23,878,1980
 
                            *** END OF RECORD ***