*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM2670650
CHEMICAL NAME           : 1-Piperazinepropanol,
                          4-(10,11-dihydro-8-(methylthio)dibenzo(b,f)thiepin-10
                          -yl)-,
                          4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate)
                          , hydrate (1:1:1)
CAS REGISTRY NUMBER     : 41931-72-0
LAST UPDATED            : 198706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H28-N2-O-S2.C23-H16-O6.H2-O
MOLECULAR WEIGHT        : 807.05
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   8-Methylthio-10-(4-(3-hydroxypropyl)piperazino)-10,11-dihydrodibenzo(b,f
     )thiepin embonate H2O
   * Oxyprothepin embonate (1:1) monohydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 137 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 38,1190,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 88600 ug/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 38,1190,1973
 
                            *** END OF RECORD ***