*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM0817610
CHEMICAL NAME           : Piperazine,
                          1-(2-(2-(ethylthio)-4-methyl-5-thiazolyl)ethyl)-4-(2-
                          methoxyphenyl)-, trihydrochloride
CAS REGISTRY NUMBER     : 89663-35-4
LAST UPDATED            : 198712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H27-N3-O-S2.3Cl-H
MOLECULAR WEIGHT        : 486.99
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-(2-(2-(Ethylthio)-4-methyl-5-thiazolyl)ethyl)-4-(2-methoxyphenyl)piper
     azine trihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 40,159,1983
 
                            *** END OF RECORD ***