*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL9830000
CHEMICAL NAME           : 1-Piperazineethanol,
                          4-(3-(trifluoromethyl)phenyl)-alpha-((4-(3-(trifluoro
                          methyl)phenyl)-1- piperazinyl)methyl)-,
                          (E)-2-butenedioate (1:2) (salt)
CAS REGISTRY NUMBER     : 67931-89-9
LAST UPDATED            : 199606
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H30-F6-N4-O.2C4-H4-O4
MOLECULAR WEIGHT        : 748.75
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,3-Bis(4-(m-trifluoromethylphenyl)piperazino)propan-2-ol difumarate
   * LJ 1152
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4203986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 36 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4203986
 
                            *** END OF RECORD ***