*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL9275800
CHEMICAL NAME           : 1-Piperazineethanol,
                          alpha-(3,4-dihydroxyphenyl)-4-p-methoxybenzyl-,
                          dihydrochloride
LAST UPDATED            : 198403
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H26-N2-O4.2Cl-H
MOLECULAR WEIGHT        : 431.40
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * alpha-(3,4-Dihydroxyphenyl)-4-p-methoxybenzyl-1-piperazineethanol  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 345 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 46,279,1957
 
                            *** END OF RECORD ***