*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL9202000
CHEMICAL NAME           : 1-Piperazineethanol,
                          4-(7,8-difluoro-10,11-dihydrodibenzo(b,f)thiepin-10-y
                          l)-, 1-oxide, dihydrochloride
CAS REGISTRY NUMBER     : 60811-16-7
LAST UPDATED            : 198703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H22-F2-N2-O2-S.2Cl-H
MOLECULAR WEIGHT        : 465.42
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4-(7,8-Difluoro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazineetha
     nol 1-oxide 2HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 510 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - paresthesis
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 41,881,1976
 
                            *** END OF RECORD ***