*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL7711000
CHEMICAL NAME           : 1-Piperazineethanol,
                          4-(1-(2-chloro-10-phenothiazinyl)-2-propyl)-,
                          3,4,5-trimethoxybenzoate
CAS REGISTRY NUMBER     : 3534-36-9
LAST UPDATED            : 199609
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C31-H36-N3-O5-S
MOLECULAR WEIGHT        : 562.76
WISWESSER LINE NOTATION : T C666 BN ISJ EG B1Y1&- AT6N DNTJ D2OVR CO1 DO1 EO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * T-82
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 58 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   21PFAR "Conferentia Hungarica pro Therapia et Investigatione in
   Pharmacologia, Societas Pharmacologyica Hungarica, 4th, Budapest, 1966,"
   Dumbovich, B., ed., Budapest, Hungary, Akademiai Kiado, 1968
   Volume(issue)/page/year: 4,167,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 1,414,1980
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3150 mg/kg/1W-I
TOXIC EFFECTS :
   Related to Chronic Data - death
REFERENCE :
   21PFAR "Conferentia Hungarica pro Therapia et Investigatione in
   Pharmacologia, Societas Pharmacologyica Hungarica, 4th, Budapest, 1966,"
   Dumbovich, B., ed., Budapest, Hungary, Akademiai Kiado, 1968
   Volume(issue)/page/year: 4,167,1968
 
                            *** END OF RECORD ***