*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL7350000
CHEMICAL NAME           : 1-Piperazineethanol,
                          4-(3-(2-chlorophenothiazin-10-yl)propyl)-, acetate
                          (ester), dihydrochloride
CAS REGISTRY NUMBER     : 146-28-1
LAST UPDATED            : 199012
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C23-H28-Cl-N3-O2-S.2Cl-H
MOLECULAR WEIGHT        : 518.97
WISWESSER LINE NOTATION : T C666 BN ISJ EG B3- AT6N DNTJ D2OV1 &GH 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(2-Acetoxyethyl)-4-(3-(2-chloro-10-phenothiazinyl)propyl)piperazine  
   dihydrochloride
   * 2-Chloro-10-(3-(4-(2-acetoxyethyl)piperazinyl)propyl)phenothiazine
   * Dartal dihydrochloride
   * Thiopropazate dihydrochloride
   * Thiopropazate hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 279 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,52,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 197 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,52,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1080 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,52,1972

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   JMSCA9 Journal of Mental Science.  (London, UK)  V.4-108, 1857-1962.  For
   publisher information, see BJPYAJ.  Volume(issue)/page/year: 106,755,1960

 
                            *** END OF RECORD ***