*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL6375050
CHEMICAL NAME           : 2,3-Piperazinedione,
                          1,4-bis((4-(2-pyrimidinylamino)phenyl)methyl)-
CAS REGISTRY NUMBER     : 77917-10-3
BEILSTEIN REFERENCE NO. : 5675766
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C26-H24-N8-O2
MOLECULAR WEIGHT        : 480.58
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,4-Bis(4-(2-pyrimidinylamino)benzyl)-2,3-dioxopiperazine
   * 1,4-Bis((4-(2-pyrimidinylamino)phenyl)methyl)-2,3-piperazinedione
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 29,1253,1981
 
                            *** END OF RECORD ***