*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL6219000
CHEMICAL NAME           : Piperazine, 3,5-dimethyl-1-nitroso-
CAS REGISTRY NUMBER     : 67774-31-6
BEILSTEIN REFERENCE NO. : 0509433
REFERENCE               : 5-23-03-00333 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H13-N3-O
MOLECULAR WEIGHT        : 143.22
WISWESSER LINE NOTATION : T6M DNTJ B1 DNO F1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 3,5-Dimethyl-1-nitrosopiperazine
   * Nitroso-3,5-dimethylpiperazine
   * N-Nitroso-3,5-dimethylpiperazine
   * 1-Nitroso-3,5-dimethylpiperazine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1450 mg/kg/29W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Blood - leukemia
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   41,1034,1981
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 ug/plate
REFERENCE :
   TCMUE9 Topics in Chemical Mutagenesis.  (Plenum Pub. Corp., 233 Spring
   Street, New York, NY 10013) V.1-    1984-  Volume(issue)/page/year:
   1,13,1984
 
                            *** END OF RECORD ***