*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL4380000
CHEMICAL NAME           : Piperazine,
                          1-(10,11-dihydro-2-(trifluoromethyl)dibenzo(b,f)thiep
                          in-10-yl)-4-methyl-, (Z)-2-butenedioate (1:1)
CAS REGISTRY NUMBER     : 57564-33-7
LAST UPDATED            : 198702
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H21-F3-N2-S.C4-H4-O4
MOLECULAR WEIGHT        : 494.57
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-(10,11-Dihydro-2-(trifluoromethyl)dibenzo(b,f)thiepin-10-yl)-4-methylp
     iperazine maleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 405 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 40,1940,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 68 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 40,1940,1975
 
                            *** END OF RECORD ***