*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL4370000
CHEMICAL NAME           : Piperazine,
                          1-(10,11-dihydro-8-(2-pyridinyloxy)dibenzo(b,f)thiepi
                          n-10-yl)-4-methyl-, (Z)-2-butenedioate, hydrate
                          (2:4:1)
CAS REGISTRY NUMBER     : 43182-92-9
LAST UPDATED            : 198703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H25-N3-O-S.2C4-H4-O4.1/2H2-O
MOLECULAR WEIGHT        : 644.70
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-(2-Pyridyloxy)-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepin 
    dimaleate 1/2H2O
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 86 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 38,1579,1973
 
                            *** END OF RECORD ***