*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL4342000
CHEMICAL NAME           : Piperazine,
                          1-(10,11-dihydro-2-nitrodibenzo(b,f)thiepin-10-yl)-4-
                          methyl-, dimethanesulfonate
CAS REGISTRY NUMBER     : 64695-19-8
LAST UPDATED            : 198702
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H21-N3-O2-S.2C-H4-O3-S
MOLECULAR WEIGHT        : 547.71
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 10-(4-Methylpiperazino)-2-nitro-10,11-dihydrodibenzo(b,f)thiepin  
   dimethanesulfonate
   * VUFB-12284
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 42,2231,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 42,2231,1977
 
                            *** END OF RECORD ***