*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL4260000
CHEMICAL NAME           : Piperazine,
                          1-(10,11-dihydro-8-methoxydibenzo(b,f)thiepin-10-yl)-
                          4-methyl-, maleate (1:1)
CAS REGISTRY NUMBER     : 19728-87-1
LAST UPDATED            : 198709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H24-N2-O-S.C4-H4-O4
MOLECULAR WEIGHT        : 456.60
WISWESSER LINE NOTATION : T C676 BS&T&J FO1 I- AT6N DNTJ D1 &QV1U1VQ -C
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Dibenzo(b,f)thiepin, 10,11-dihydro-8-methoxy-10-(4-methylpiperazino)-,  
   maleate
   * 1-(10,11-Dihydro-8-methoxydibenzo(b,f)thiepin-10-yl)-4-methylpiperazine  
   maleate
   * 8-Methoxyperathiepin maleate
   * Octometothepin maleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 48 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 40,2667,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 51 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 36,2226,1971
 
                            *** END OF RECORD ***