*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL4254500
CHEMICAL NAME           : Piperazine,
                          1-(4,5-dihydro-8-fluorothieno(2,3-b)(1)benzothiepin-4
                          -yl)-4-methyl-, (Z)-2-butenedioate (1:1)
CAS REGISTRY NUMBER     : 73248-78-9
LAST UPDATED            : 198709
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H19-F-N2-S2.C4-H4-O4
MOLECULAR WEIGHT        : 450.58
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-Fluoro-4-(4-methylpiperazino)-4,5-dihydrothieno(2,3-b)-1-benzothiepin  
   maleate
   * VUFB-12351
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 108 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 44,2997,1979
 
                            *** END OF RECORD ***