*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL3564000
CHEMICAL NAME           : Piperazine,
                          1-(3,4-dichlorophenyl)-4-(2-(4-methyl-5-thiazolyl)eth
                          yl)-, trihydrochloride
CAS REGISTRY NUMBER     : 89663-28-5
LAST UPDATED            : 198712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H19-Cl2-N3-S.3Cl-H
MOLECULAR WEIGHT        : 465.72
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(3,4-Dichlorophenyl)-4-(2-(4-methyl-5-thiazolyl)ethyl)piperazine  
   trihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 340 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 40,159,1983
 
                            *** END OF RECORD ***