*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL3503000
CHEMICAL NAME           : Piperazine,
                          1-(3-dibenzo(b,e)thiepin-6(11H)-ylidenepropyl)-4-meth
                          yl-, hydrochloride
CAS REGISTRY NUMBER     : 102233-02-3
LAST UPDATED            : 198706
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H26-N2-S.Cl-H
MOLECULAR WEIGHT        : 387.02
WISWESSER LINE NOTATION : T C676 BY IS JHJ BU3- AT6N DNTJ D1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(3-Dibenzo(b,e)thiepin-6(11H)-ylidenepropyl)-4-methylpiperazine  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45500 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Vascular - BP elevation not characterized in autonomic section
   Lungs, Thorax, or Respiration - bronchiolar dilation
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 13,1039,1963
 
                            *** END OF RECORD ***