*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL1569500
CHEMICAL NAME           : Piperazine,
                          1-(8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4
                          -(2-methoxyethyl)-, maleate (1:1)
CAS REGISTRY NUMBER     : 101040-81-7
LAST UPDATED            : 199204
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H25-Cl-N2-O-S.C4-H4-O4
MOLECULAR WEIGHT        : 505.07
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-(8-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-(2-methoxyethyl)pi
     perazine
   *   1-(8-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-(2-methoxyethyl)pi
     perazine maleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 269 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 50,1070,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 50,1070,1985
 
                            *** END OF RECORD ***