*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL1553000
CHEMICAL NAME           : Piperazine,
                          1-(8-chlorodibenzo(b,f)thiepin-10-yl)-4-methyl-
CAS REGISTRY NUMBER     : 22431-21-6
BEILSTEIN REFERENCE NO. : 0625720
REFERENCE               : 5-23-02-00448 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H19-Cl-N2-S
MOLECULAR WEIGHT        : 342.91
WISWESSER LINE NOTATION : T C676 BS&T&J FG I- AT6N DNTJ D1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(8-Chlorodibenzo(b,f)thiepin-10-yl)-4-methylpiperazine
   * 8-Chloro-10-(4-methylpiperazino)dibenzo(b,f)thiepin
   * Dehydroclothepin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 44 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 40,719,1975
 
                            *** END OF RECORD ***