*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL0800000
CHEMICAL NAME           : 1-Piperazinecarboxamide,
                          4-(3-(2-chlorophenothiazin-10-yl)propyl)-
CAS REGISTRY NUMBER     : 14053-35-1
LAST UPDATED            : 199012
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C20-H23-Cl-N4-O-S
MOLECULAR WEIGHT        : 402.98
WISWESSER LINE NOTATION : T C666 BN ISJ EG B3- AT6N DNTJ DVZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 9153 RP
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 670 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMPYAT Annales Medico-Psychologiques.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-Series 11, V.2, 1843-1921; V.80-    1922-
   Volume(issue)/page/year: 119,736,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 181 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMPYAT Annales Medico-Psychologiques.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-Series 11, V.2, 1843-1921; V.80-    1922-
   Volume(issue)/page/year: 119,736,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1745 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMPYAT Annales Medico-Psychologiques.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-Series 11, V.2, 1843-1921; V.80-    1922-
   Volume(issue)/page/year: 119,736,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#00210
 
                            *** END OF RECORD ***